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Similar to carbon chain lengths, the double bonds in unsaturated fatty acid carbon chains induce conformational changes in PPARs and trigger PPAR-dependent intracellular signals in a manner different from the single bonds in saturated fatty acids [26]

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Other pieces of BD pathogenesis, including inflammation, mitochondrial dysfunction, calcium dysregulation, neurotransmission disturbance, and affection of synaptic plasticity and myelination, are either a preface or an aftermath of iron dysregulation

This proposed roundtable session draws on lessons from multiple European Commission funded DT research projects from across Europe including BIPED (Building Intelligent Positive Energy Districts), TIPS4PED and Twin4Resilience

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